If a male native is born in daytime and in his horoscope - Lagna, Sun and Moon are all placed in odd signs then Mahabhagya Yoga is formed in the horoscope. Also, if a female native is born during nighttime and in her horoscope; Lagna, Sun and Moon are all placed in even signs, Mahabhagya Yoga is formed in the horoscope. This yoga can bless the native with good results related to profession, fortune, authority, fame and a number of other good things.
The first house can be vacant or it should be occupied by one or more than one benefic planet. If the first house is occupied by malefic planet/planets; Mahabhagya Yoga may not be formed or it may not do much good; depending on the overall horoscope under consideration.